INNATE IMMUNE MEMORY IN MONOCYTES AND MACROPHAGES: THE POTENTIAL THERAPEUTIC STRATEGIES FOR ATHEROSCLEROSIS

Atherosclerosis is a complex metabolic disease characterized by the dysfunction of lipid metabolism and chronic inflammation in the intimal space of the vessel.As the most abundant innate immune cells, monocyte-derived macrophages play a pivotal role in the inflammatory response, cholesterol metabolism, and foam cell formation.In recent decades, it

The Asia-Pacific region is extremely vulnerable to climate variability and change.This reflects high exposure to hydroclimatic hazards such as tropical cyclones, floods, droughts, and heatwaves.Rapidly growing cities and low-lying coastal zones/estuaries also face threats from sea level rise and storm surges.However, climate model projections remai